Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist

Semaglutide and Tirzepatide are highly effective medications for managing obesity and supporting weight loss. They work by mimicking natural hormones—GLP-1, and in the case of Tirzepatide, both GLP-1 and GIP—that help regulate appetite, blood sugar, and metabolism.

Benefits

  • Significant weight loss

  • Improved blood sugar control

  • Enhanced insulin sensitivity

  • Reduced cardiovascular risk (Semaglutide)

  • Greater weight loss and glucose control with dual-action (Tirzepatide)

Potential Side Effects

  • Nausea, vomiting, diarrhea, or constipation (most common when starting treatment)

  • Possible increased risk of pancreatitis

  • FDA boxed warning for thyroid tumors (seen in animal studies, not humans)

Safety Considerations

These medications may not be appropriate for people with a history of:

  • Pancreatitis

  • Certain thyroid cancers (including medullary thyroid carcinoma)

Before starting therapy, it’s important to discuss your medical history and goals with a qualified provider to determine if GLP-1 or GIP medications are the right fit for you.